Detalhe da pesquisa
1.
Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes.
Nature
; 625(7994): 385-392, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-38123683
2.
Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress.
Mol Cell
; 81(20): 4191-4208.e8, 2021 10 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34686314
3.
Spatial and temporal control of mitochondrial H2 O2 release in intact human cells.
EMBO J
; 41(7): e109169, 2022 04 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35146782
4.
AIFM1 is a component of the mitochondrial disulfide relay that drives complex I assembly through efficient import of NDUFS5.
EMBO J
; 41(17): e110784, 2022 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35859387
5.
Alterations of redox and iron metabolism accompany the development of HIV latency.
EMBO J
; 39(9): e102209, 2020 05 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32157726
6.
SARM1 deletion delays cerebellar but not spinal cord degeneration in an enhanced mouse model of SPG7 deficiency.
Brain
; 146(10): 4117-4131, 2023 10 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37086482
7.
Organ Protection by Caloric Restriction Depends on Activation of the De Novo NAD+ Synthesis Pathway.
J Am Soc Nephrol
; 34(5): 772-792, 2023 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36758124
8.
CLPP deficiency ameliorates neurodegeneration caused by impaired mitochondrial protein synthesis.
Brain
; 145(1): 92-104, 2022 03 29.
Artigo
Inglês
| MEDLINE | ID: mdl-35240691
9.
DNA polymerase gamma mutations that impair holoenzyme stability cause catalytic subunit depletion.
Nucleic Acids Res
; 49(9): 5230-5248, 2021 05 21.
Artigo
Inglês
| MEDLINE | ID: mdl-33956154
10.
DARS2 is indispensable for Purkinje cell survival and protects against cerebellar ataxia.
Hum Mol Genet
; 29(17): 2845-2854, 2020 10 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32766765
11.
The Mouse Heart Mitochondria N Terminome Provides Insights into ClpXP-Mediated Proteolysis.
Mol Cell Proteomics
; 19(8): 1330-1345, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32467259
12.
A C. elegans model for neurodegeneration in Cockayne syndrome.
Nucleic Acids Res
; 48(19): 10973-10985, 2020 11 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33021672
13.
Mitochondrial Dysfunction Combined with High Calcium Load Leads to Impaired Antioxidant Defense Underlying the Selective Loss of Nigral Dopaminergic Neurons.
J Neurosci
; 40(9): 1975-1986, 2020 02 26.
Artigo
Inglês
| MEDLINE | ID: mdl-32005765
14.
Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein.
J Mol Cell Cardiol
; 154: 41-59, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33549681
15.
Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.
EMBO Rep
; 20(4)2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30886000
16.
CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels.
EMBO J
; 35(23): 2566-2583, 2016 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27797820
17.
CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis.
EMBO Rep
; 19(5)2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29588285
18.
DARS2 protects against neuroinflammation and apoptotic neuronal loss, but is dispensable for myelin producing cells.
Hum Mol Genet
; 26(21): 4181-4189, 2017 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28985337
19.
Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson's disease.
Hum Mol Genet
; 25(24): 5365-5382, 2016 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27794539
20.
Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt.
EMBO Rep
; 17(7): 953-64, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27154400